Cariñena,the largest and oldest of the Aragonese DOs, was one of Spain's earliest areas to be demarcated, in 1932. It has given its name to the grape of the same name, called the Mazuelo elsewhere in northern Spain and the Carignan in France.

The last decade has seen fast development thanks to fusions between small bodegas and cooperatives, and the reshaping of wines to modern tastes. The wines have become bigger and bolder although production of the traditional famed rosés and Moscatels has continued.

Exports have quadrupled since 1995. A new government research station has also been helping to push forward production.